Interleukin-2 ELISA kit is a method for determining in vitro quantitative amounts of interleukin-2 (IL-2) in human serum, cell culture supernatant, plasma (heparin, citrate, EDTA). This assay has a minimum detection limit of < 0.1 pg/ml.
Interleukin-2 (IL-2) which was also originally known as T-cell growth factor, is produced by antigen- or lectin-activated T cells and is a powerfully immune-regulatory lymphokine. It is not only formed by the stimulation of mature T lymphocytes but also constitutively by a number of T-cell lymphoma cell lines. It has vital functions in the regulation of activation and proliferation of lymphocytes which have already been primed by antigens. Interleukin-2 also has a central role in the expansion of B-cells, T-cells and natural killer cells during certain phases of their response.
The following interleukin-2 ELISA kit is ideal for analysing many different diagnostic applications. The human gene for interleukin 2 (IL-2) is located on chromosome 4. Human IL-2 is made up of 153 amino acids in the precursor form or 133 amino acids in the mature form and it is a 15.5KDa glycoprotein. Due to its central role in the immune response process, IL-2 has become a very important for many therapeutic and diagnostic implications. There is evidence to suggest that it may also display anti-tumoral effects which can be particularly useful in cancer therapy. By monitoring the levels of interleukin 2 in serum this can provide a better insight into several pathological situations such as rheumatoid arthritis, transplant rejection, cancer, multiple sclerosis, type I diabetes, systemic lupus erythematosus and infectious diseases. However, this issue with IL-2 toxicity is still a major concern and merit investigation. This interleukin-2 ELISA kit offers a sensitivity level of 0.1 pg/ml and it can be used to measure human samples of plasma, cell culture supernatant and serum.
The minimum detection sensitivity level of IL-2 (interleukin-2) using current human interleukin-2 ELISA kit was approximately 0.1 pg/ml. The dynamic range for this assay is 15.6 – 1,000 pg/ml.
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- Full Name: Interleukin-2 (IL-2) ELISA Kit
- Reactivity: Human
- Sample Type: Serum, Cell Culture Supernatant, Plasma (Citrate, EDTA, Heparin)
- Sensitivity: < 0.1 pg/ml