Vascular Cell Adhesion Molecule-1 (VCAM-1) ELISA Kit

  • Created on the 2 May, 2017.


Human VCAM-1 ELISA kit that is designed for detecting in vitro quantitative levels of vascular cell adhesion molecule-1 (CD106, VCAM-1) in human serum, cell lysates, biological fluids, cell culture supernatant and plasma. This assay has a minimum sensitivity limit of 0.03 ng/ml.


VCAM-1 is also known as CD106, having a main function as a cell adhesion molecule. The protein has a major role in mediating adhesion of monocytes, lymphocytes, basophils, eosinophils and vascular endothelium cells. Some of VACAM-1 other functions include signal transduction of leukocyte-endothelial cells and a facilitating the development of rheumatoid arthritis and atherosclerosis. The expression of VCAM-1 has also been identified in a number of other cell types such as smooth muscle cells. Increased expression of VCAM1 has been found to be linked to a variety of chronic inflammatory conditions, this makes this molecule an ideal target for intervention. There are some melanoma cells which are able to use VCAM-1 in order to adhere to the endothelium, it has also be found to participate in the recruitment of monocyte to a number of atherosclerotic sites.

VCAM-1 gene consists of 6-7 immunoglobulin domains which can be expressed on both large and small blood vessels following cytokine stimulation of endothelial cells. The gene product is a type I membrane protein (cell surface sialoglycoprotein), a member of the Ig superfamily. Presently, in humans two RNA transcripts which encode different isoforms (alternatively spliced) have been identified. The following VCAM-1 ELISA kit is ideal for measuring many types of diagnostic applications.


The minimum detection sensitivity level of vascular cell adhesion molecule-1 or CD106 using current human VCAM-1 ELISA kit was 0.03 ng/ml. The dynamic range for this assay is 0.781 – 50 ng/ml.


  1. Emerging properties of adhesion complexes: what are they and what do they do? Trends Cell Biol. (2015) 25 (7): 388-97. Review. Humphries J.D., et al.
  2. Biomarkers in Rheumatoid Arthritis, what is new? J Med Life. (2016) 9 (2): 144-8. Review. Gavrilă B.I., et al.
  3. Cellular adhesion molecules on vascular smooth muscle cells. Cardiovasc Res. (1999) 41 (2): 395-401. Review. Braun M., et al.


  • Full Name: Vascular Cell Adhesion Molecule-1 (VCAM-1) ELISA Kit
  • Reactivity: Human
  • Sample Type: Cell Lysates, Cell Culture Supernatant, Serum, Plasma, Other Biological Fluids
  • Sensitivity: 0.03 ng/ml



Your secretory IgA ELISA kit gave good results and I was also really impressed with how quickly we received it.

L. Johnston
PhD Student / University of Glasgow

It is refreshing to know that you have a technical team that is very knowledgeable. I have already recommended your company to other researchers in our department.

Dr. P. Anderson
Lecturer / University College London (UCL)

I am a first time user and found that your instruction manual was very easy to follow. The insulin ELISA kit performed well and I was happy with the results that were generated.

J. Thomas
Senior Technician / Addenbrooke’s Hospital

I carried out a pilot study comparing the performance of many ELISA kits from different suppliers and found your kits to be one of the better performers. We observed good linearity and tight replicates.

Dr. C. Davies
Lead Scientists / AstraZeneca

You are my first point of contact when I am looking to purchase ELISA kits. You have such an easy and simple system, yet it is very effective.

A. Shaw
Purchasing / University of Oxford