Human Varicella zoster IgG ELISA kit is designed for analysing in-vitro quantitative concentrations of human IgG class antibodies against Varicella zoster virus using serum or plasma. This assay has a minimum analytical sensitivity limit of 1.01 U/ml.
Varicella-zoster virus (VZV) is an infectious disease which can cause chickenpox (varicella) during childhood and herpes zoster (singles) during adulthood. VZV is also referred to by many names, such as varicella virus, zoster virus, chickenpox virus and human herpesvirus type 3 (HHV-3). VZV predominately multiplies within the lungs and it can cause a number of different symptoms (pneumonia, bronchitis and encephalitis). Following the primary infection of chickenpox, the virus is found to go dormant in the nerve cells (examples of these include dorsal root ganglia, cranial nerve ganglia and autonomic ganglia). VZV is also very closely related to the herpes simplex viruses (HSV), displaying a high level of genome homology. The virons have a diameter of 180–200 nm, a lipid envelope enclosing the nucleocapsid and the DNA is a double stranded molecule which is 125,000 nucleotides long. Serological screen can be performed to test for IgG-class antibodies to VZV, this can help to identify non-immune individuals. Also, the identification of IgM-class antibodies to VZV can indicate a recent or acute infection but this needs to be correlated with clinical presentation.
The minimum detection sensitivity level of IgG antibodies to Varicella zoster virus using current human Varicella zoster IgG ELISA kit was 1.01 U/ml. The dynamic range for this assay is 1.0 – 150.0 U/ml.
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- Full Name: Varicella Zoster IgG ELISA Kit
- Reactivity: Human
- Sample Type: Plasma, Serum
- Sensitivity: 1.01 U/ml