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Triiodothyronine (T3) ELISA Kit

  • Created on the 26 January, 2017.

BACKGROUND

Thyroid hormones play essential roles in the proper development and differentiation of many cells within the human body. Triiodothyronine (T3) is a tyrosine-based hormone that is produced by the thyroid gland and is a useful marker for hyperthyroidism and hypothyroidism diagnosis. One of the major carrier of circulating thyroid hormones is thyroxine-binding globulin (TGB). There are a number of pathological and physiological stimuli that can influence thyroid hormone synthesis and any deficiencies or excess of thyroxine can cause many disorders. The level of T3 is found to be normal in individuals with euthyroid, whereas in hyperthyroid patients it is increased and in hypothyroid patients it is decreased.

INTENDED USE

Triiodothyronine ELISA kit can be used to reliably detect levels of total T3 present in serum or plasma samples. The detection sensitivity of this assay is 0.1 ng/ml.

SENSITIVITY

This triiodothyronine ELISA kit has a minimum detectable sensitivity concentration of 0.1 ng/ml. The assay dynamic range for this kit was determined to be between 0.5 – 10 ng/l.

REFERENCES

  1. Clinical usefulness of ELISA technique in the assessment of thyroid function. West Afr J Med (1990) 9(4):258-63. Agharanya JC.
  2. Thyroid function in very low birth weight infants: effects on neonatal hypothyroidism screening. J Pediatr (1996)128(4):548-54. Frank JE, Faix JE, Hermos RJ, Mullaney DM, Rojan DA, Mitchell ML, Klein RZ.
  3. Thyroid functions in patients with various chronic liver diseases. Endocrinol Jpn (1988)35(3):357-69. Shimada T, Higashi K, Umeda T, Sato T.
  4. Total serum levels of triiodothyronine (T3) thyroxine (T4) and thyrotropine (TSH) in school going children of Dibrugarh district: an endemic goiter region of Assam. Indian J Physiol Pharmacol (1997) 41(2):167-70. Thakur C, Saikia TC, Yadav RN.

ADDITIONAL INFORMATION

  • Description: Triiodothyronine (T3) ELISA Kit
  • Reactivity: Human
  • Sample Type: Serum, Plasma
  • Sensitivity: 0.1 ng/ml

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