- Created on the 29 June, 2017.
Sjögren syndrome type A antigen (SS-A) is an extractable nuclear antigen (ENA) that is composed of 52 kD and 60 kD protein antigens which are combined with cytoplasmic RNA species. SS-A 60 is a major component of the cytoplasmic ribonucleoprotein complex I humans and it is found the both SS-A 60 and SS-A-52 proteins have the ability to bind smaller RNAs and ribonucleoprotein particles that can be present in the nucleus or the cytoplasm. Autoantibodies against SS-A 60 are mainly found in patients with lupus erythematosus and Sjögren’s syndrome, these autoantibodies also predominately appear in conjunction with SS-A 52 and SS-B antibodies. This ELSA assay is particularly helpful in the differential diagnosis and monitoring of systemic rheumatic inflammatory autoimmune diseases.
Human SS-A 60 ELISA kit can be used for detecting in-vitro quantitative levels of IgG autoantibodies to Sjögren syndrome type A antigen 60 (SS-A 60, anti SS-A 60) in human serum or plasma. This assay has a minimum analytical sensitivity limit of 0.5 U/ml.
The minimum detection sensitivity level of human Sjögren syndrome type A antigen 60 (anti SS-A 60, SS-A 60, anti-Ro) IgG autoantibodies using this human SS-A 60 ELISA kit was 0.5 U/ml. The dynamic assay range for this kit is 12.5 – 200.0 U/ml.
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- Full Name: SS-A 60 Ab ELISA Kit
- Reactivity: Human
- Sample Type: Plasma, Serum
- Sensitivity: 0.5 U/ml