Prothrombin Screen ELISA Kit

  • Created on the 16 June, 2017.


Human prothrombin screen ELISA kit is useful for sceening in-vitro quantitative concentrations of IgG, IgA and IgM autoantibodies to prothrombin in human serum or plasma. This assay has a minimum analytical sensitivity limit of 1.0 U/ml.


Prothrombin is a carbohydrate-protein compound which is transformed to thrombin using the enzyme prothrombinase, thrombin is then responsible for transforming fibrinogen into fibrin. Platelets and fibrin can cause the formation clots, a process known as coagulation and this is important during bleeding. A deficiency in prothrombin which is known as hypoprothrombinemia is defined by its prolonged tendency to bleeding. The following prothrombin screen ELISA kit is intended to be used for many different diagnostic applications.


The minimum detection sensitivity level of IgM, IgG and IgA antibodies against prothrombin using current human prothrombin screen ELISA kit was 1.0 U/ml. The dynamic range for this assay is 6.3 – 100.0 U/ml.


  1. Mixing studies for abnormal coagulation screen – the current trend. Clin Chem Lab Med. (2017) 55 (3): e54-e55. Mohammad E. and Thachil J.
  2. IgG, IgA, IgM, and IgD antiglobulins in juvenile rheumatoid arthritis. Ann Rheum Dis. (1974) 33 (1): 32-4. Florin-Christensen A., et al.
  3. Utility of antiphosphatidylserine/prothrombin and IgA antiphospholipid assays in systemic lupus erythematosus. J Rheumatol. (2013) 40 (3): 282-6. Akhter E., et al.
  4. Selected autoantibodies and normal-tension glaucoma. Med Sci Monit. (2014) 20: 1201-9. Skonieczna K., et al.


  • Full Name: Prothrombin Screen ELISA Kit
  • Reactivity: Human
  • Sample Type: Plasma, Serum
  • Sensitivity: 0 U/ml



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