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LRG ELISA Kit (Mouse)

  • Created on the 20 August, 2018.

INTENDED USE

Mouse LRG ELISA kit is designed for analysing qualitative levels of leucine rich alpha2-glycoprotein (alpha-2-glycoprotein, LRG) in mouse serum, cell culture supernatant and plasma. This assay has a minimum sensitivity detection limit of 0.06 ng/ml.

BACKGROUND

Leucine rich alpha2-glycoprotein (LRG) has many functions which can include: protein to protein interactions, cell adhesion, cell development and signal transduction. It is member of a protein family which contains a large number of leucine repeats and its levels in serum have been found to be increase in rheumatoid arthritis patients and in the cerebrospinal fluid in iNPH.

SENSITIVITY

The minimum sensitivity detection limit of mouse leucine rich alpha2-glycoprotein (LRG, alpha-2-glycoprotein) using current mouse LRG ELISA kit is 0.06 ng/ml. The dynamic range for this assay is 0.25 – 16.0 ng/ml.

REFERENCES

  1. Lrg participates in lipopolysaccharide preconditioning-induced brain ischemia injury via TLR4 signaling pathway. J Mol Neurosci. (2014) 54 (1): 20-6. Gong G., et al.
  2. ELISA for human serum leucine-rich alpha-2-glycoprotein-1 employing cytochrome c as the capturing ligand. J Immunol Methods. (2008) 336 (1): 22-9. Weivoda S., et al.
  3. Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines. Oncotarget. (2015) 6 (13): 11009-22. Takemoto N., et al.
  4. Leucine rich α-2 glycoprotein is a potential urinary biomarker for renal tubular injury. Biochem Biophys Res Commun. (2018) 498 (4): 1045-1051. Lee H., et al.

ADDITIONAL INFORMATION

  • Full Name: LRG ELISA Kit (Mouse)
  • Reactivity: Mouse
  • Sample Type: Plasma (EDTA), Serum, Cell Culture Supernatant
  • Sensitivity: 0.06 ng/ml

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