Leishmania ELISA Kit

Full Name: Leishmania ELISA Kit
Reactivity: Veterinary Mammalian
Sample Type: Serum
Sensitivity: Cut-Off

BACKGROUND

Leishmania is an infectious condition, typically spread through sand fly bites and caused by many species of parasites. It can affect both dogs and humans, leading to a disease called visceral leishmaniasis. Some species of Leishmania are less contagious than others; for example, L. infantum is the most common form of the disease in countries like Brazil and Peru where sand fly bites are more common. This type does not cause systemic symptoms of the disease. Over time, Leishmaniasis may get worse and affect other organs causing anemia, joint pain and soreness, or a possible tumor-like mass in the abdomen (gastrointestinal tumor). Symptoms of the disease can be treated and managed for a time if caught early. The best course of treatment for advanced stages is to give supportive care in an effort to extend life.

Leishmania parasite is spread by sand flies from one person to another close to their habitat. The parasites are transmitted when a sand fly bites an infected person and then picks up sand from its surroundings. This process can happen through direct contact between the infected individual and a sand fly or through indirect contact with an object that has been contaminated with parasite urine. White blood cells are sent by the body’s immune system to kill the parasites when Leishmania infection symptoms appear. The area, however, becomes inflamed and painful.

INTENDED USE

Leishmania ELISA kit is intended for analysing qualitative levels of antibodies against Leishmania (anti-Leishmania) in different veterinary mammalian serum. This assay has a minimum sensitivity to a cut-off.

SENSITIVITY

The minimum sensitivity detection limit of antibodies to Leishmania (anti-Leishmania) using current Leishmania ELISA kit is to a cut-off point. Please contact us for the protocol insert for more details.

REFERENCES

1. Evaluation of indirect immunofluorescence antibody test and enzyme-linked immunosorbent assay for the diagnosis of infection by Leishmania infantum in clinically normal and sick cats. Exp Parasitol. (2014) 147: 54-9. Chatzis MK, et al.
2. Recombinant Leishmania-infantum heat shock protein 83 for the serodiagnosis of cutaneous, mucosal, and visceral leishmaniases. Am J Trop Med Hyg. (2014) 90 (5): 860-5. Celeste BJ, et al.
3. Evaluation of an ELISA for canine leishmaniasis immunodiagnostic using recombinant proteins. Parasite Immunol. (2012) 34 (1): 1-7. de Souza CM, et al.

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