- Created on the 12 March, 2017.
Interleukin-9 (IL-9) is a pro-inflammatory cytokine which was originally identified as a 40KD glycoprotein with T-cell growth factor activity in mice. The human IL-9 was later discovered on the basis of its high level of homogeneity with the gene of mouse IL-9. Human IL-9 has be strongly associated with human malignant lymphoma and also demonstrated to be a stimulator for hematopoiesis. Furthermore, its expression has been found to be implicated with autoimmune and many allergic diseases.
Interleukin-9 is well studied as a therapeutic target for asthma due to it being implication with the disease. IL-9 can be produced by Th2 cells which are under the stimulation of TGF-b and IL-4. This lineage has been shown to play vital role in the differentiation of Th17 cells and Treg function. There has been a renewed attention on IL-9 in recent years due to a unique type of innate lymphoid cells which have been discovered in mice where the main cell types expressing IL-9 secreting and in vivo cells present with the skin appear to mediate the inhibition of melanoma growth. These same interleukin-9 secreting cells have now also been identified in human and are being evaluated as a new tumour treatment strategy.
Interleukin-9 ELISA kit is designed for detecting in vitro quantitative concentrations of interleukin-9 (IL-9) present in human serum, plasma, cell culture supernatant and many other biological fluids. This assay has a minimum detection limit of < 0.343 pg/ml.
The minimum detection sensitivity level of interleukin-9 (IL-9) using this human interleukin-9 ELISA kit was approximately 0.343 pg/ml. The dynamic assay range for this kit is 0.78 – 50 pg/ml.
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- Full Name: Interleukin-9 (IL-9) ELISA Kit
- Reactivity: Human
- Sample Type: Serum, Plasma, Cell Culture Supernatant, Other Biological Fluids
- Sensitivity: < 0.343 pg/ml