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Influenza B IgG ELISA Kit

  • Created on the 23 August, 2017.

BACKGROUND

Influenza B viruses have only been identified to infect humans and seals and at present there are two co-circulating lineages of the Influenza B virus which are classified according to their antigenic properties on glycoprotein hemagglutinin surface. The two lineages are referred to either B/Victoria/2/87-like or B/Yamagata/16/88-like viruses. The genome of the influenza B virus is approx. 14548 nucleotides long and made up of eight fragments of linear single stranded negaitive-sense RNA. The influenza B virus capsid is spherical and filamentous, having over 500 surface projection of hemagglutinin and neuraminidase.

INTENDED USE

Human influenza-B IgG ELISA kit is a method for analysing in-vitro quantitative concentrations of human IgG antibodies to influenza B using plasma or serum. This assay has a minimum analytical sensitivity limit of 1.07 U/ml.

SENSITIVITY

The minimum detection sensitivity level of human influenza B IgG using this human influenza-B IgG ELISA kit was 1.07 U/ml. The dynamic assay range for this kit is 1.0 – 175.0 U/ml.

REFERENCES

  1. Influenza A and B virus IgG and IgM serology by enzyme immunoassays. Epidemiol Infect. (1987) 99 (1): 55-64. Koskinen P., et al.
  2. Intranasal immunization with influenzaantigens conjugated with cholera toxin subunit B stimulates broad spectrum immunity against influenza viruses. Hum Vaccin Immunother. (2014) 10 (5): 1211-20. Li J., et al.
  3. Laboratory and epidemiologic assessment of a recent influenza B outbreak. J Med Virol. (1988) 25 (3): 361-8. King J.C. Jr, et al.
  4. Monoclonal antibodies for the rapid diagnosis of influenza-B virus infections by ELISA: production and characterization. Clin Diagn Virol. (1995) 4 (1): 27-42. Glikmann G., et al.

ADDITIONAL INFORMATION

  • Full Name: Influenza B IgG ELISA Kit
  • Reactivity: Human
  • Sample Type: Plasma, Serum
  • Sensitivity: 1.07 U/ml

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