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Influenza A IgG ELISA Kit

  • Created on the 23 August, 2017.

BACKGROUND

There are four different types of influenza viruses (A, B, C and D) and only types A and B are responsible for causing human diseases. In general, wild aquatic birds are the natural host for majority of influenza A type viruses (such as swans, geese, ducks, shorebirds and gulls). Influenza A viruses can be divided into subtypes, either hemagglutinin (HA) or neuraminidase (NA). Currently, there are 18 HA subtypes and 11 NA subtypes which have been identified, also it is possible to have a large number of different combinations of HA and NA proteins. However, only two influenza A virus subtypes (for example H1N1 and H3N2) are presently found to be in general circulation among people. Influenza viruses belonging to the family Orthomyxoviridae and also known as the flu.

INTENDED USE

Human influenza-A IgG ELISA kit is designed for detecting in-vitro quantitative amounts of human IgG antibodies to influenza A in serum and plasma samples. This assay has a minimum analytical sensitivity limit of 1.1 U/ml.

SENSITIVITY

The minimum detection sensitivity level of human influenza A IgG using this human influenza-A IgG ELISA kit was 1.1 U/ml. The dynamic assay range for this kit is 1.0 – 150.0 U/ml.

REFERENCES

  1. A pilot study showing differences in glycosylation patterns of IgG subclasses induced by pneumococcal, meningococcal, and two types of influenzavaccines. Immun Inflamm Dis. (2014) 2 (2): 76-91. Vestrheim A.C., et al.
  2. Detection of influenza A/H1N1-specific human IgG-secreting B cells in older adults by ELISPOT assay. Viral Immunol. (2014) 27 (2): 32-8. Painter S.D., et al.
  3. Influenza A and B virus IgG and IgM serology by enzyme immunoassays. Epidemiol Infect. (1987) 99 (1): 55-64. Koskinen P., et al.
  4. Serum IgGsubclass responses of humansto inactivated and live influenza A vaccines compared to natural infections with influenza A. J Med Virol. (1990) 30 (2): 92-6. Hocart M.J., et al.

ADDITIONAL INFORMATION

  • Full Name: Influenza A IgG ELISA Kit
  • Reactivity: Human
  • Sample Type: Plasma, Serum
  • Sensitivity: 1.1 U/ml

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