Bacterial diseases occur when harmful bacteria is able to enter areas of the body which are normally sterile (e.g. in the bladder) or when they are able to crowd out helpful bacteria (e.g. in the intestines). Harmful bacteria are called pathogens and are small tiny organisms that are referred to as microbes. These microbes cannot be seen without the aid of the microscope and are able to enter to body through many means including inhalation into the nose and lungs, ingestion through food and through sexual contact. The general symptoms of bacterial diseases are chills and fever, but it can lead to a number of serious and in many cases life-threatening complications. Examples of this include kidney failure, bacteremia (blood poisoning), toxic shock syndrome, syphilis and urinary tract infections. Permanent neurological damage such as brain damage, paralysis, hearing loss and blindness can also occur. It is worth pointing out that the vast majority of bacteria actually do not cause any disease and in fact many bacteria are actually helpful and even necessary for good health.
Bacterial diseases can be put into three kinds of groupings:
- Vector-Borne Disease: Classical example of this is borrelia (Lyme disease). This is a common tick-borne disease that is transmitted to humans as a result of a bite of infected ticks from the genus lxodes species. It is a multi-systemic disease but can be treated in all stages using antibiotics. Usually, the borrelia IgM and IgG ELISAs combine native and recombinant proteins in order to achieve superior specificity and sensitivity.
- Sexually Transmitted Disease: Common examples include syphilis and chlamydia, both of which are transmitted between humans through the actions of human sexual behaviour. Treponema pallidum is another infectious systemic disease which is contagious – it is the causative organism of syphilis. Due to its excellent performance and positive results the ELISA kit method has become the gold standard for the diagnosis of syphilis.
- Vaccination Management: Common examples include diphtheria, tetanus and pertussis. Since these diseases have not been eradicated yet, children are routinely vaccinated against these, DTaP vaccination is one of the recommended childhood immunisations. Serological test are used to verify presence of protective antibodies and also help in deciding if basic or a booster form of immunisation is required.
Popular Bacterial Disease ELISA Kits
- Bordetella Pertussis IgG ELISA Kit
- Borrelia Burgdorferi IgM ELISA Kit
- Brucella Abortus IgM ELISA Kit
- Chlamydia Trachomatis IgA ELISA Kit
- Chlamydia Pneumoniae IgG ELISA Kit
- Tetanus Toxoid IgG ELISA Kit
- Diphtheria Toxin IgG ELISA Kit
- Helicobacter Pylori IgA ELISA Kit
- Mycoplasma Pneumoniae IgM ELISA Kit
- Mycobacterium Tuberculosis IgG ELISA Kit
- Treponema Pallidum (Syphilis) IgM ELISA Kit