Human HSV 1/2 IgM ELISA kit can be used for measuring in-vitro quantitative levels of human IgM antibodies against herpes simplex virus 1 and 2 (HSV 1 and 2 IgM) in serum and plasma samples. This assay has a minimum analytical sensitivity limit of 1.12 U/ml.
Herpes simplex virus (HSV) types 1 and 2 are known to produce infection which can range from mild stomatitis to disseminated and fatal disease, they belong to the Herpesviridae family. Clinical conditions that have been associated with HSV infection include keratitis, aseptic meningitis, vesicular skin eruptions, encephalitis, gingivostomatitis, disseminated primary infection, neonatal herpes and genital tract infections. HSV 1 is mostly found in orolabial infection whereas HSV 2 causes primarily urogenital infections, however, HSV 1 and 2 infections are found to differ greatly in severity and also in clinical manifestations. For typing of HSV 1/HSV 2 indirect immunofluorescence or Western blots can be performed. HSV-specific antibodies (IgG and IgM) can be used through ELISA assays for monitoring purpose, however, the “gold standard” for diagnosis of HSV infection still involves virus isolation from tissue culture.
The minimum detection sensitivity level of IgM antibodies directed to herpes simplex virus 1 and 2 (HSV 1 and 2-IgM) using current human HSV 1/2 IgM ELISA kit was 1.12 U/ml. The dynamic range for this assay is 1.0 – 100.0 U/ml.
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- Full Name: Herpes Simplex Virus 1/2 IgM ELISA Kit
- Reactivity: Human
- Sample Type: Plasma, Serum
- Sensitivity: 1.12 U/ml