Human HSV 1/2 IgG ELISA kit is intended for in-vitro quantitative detection of human IgG antibodies to herpes simplex virus 1 and 2 (HSV 1 and 2 IgG) in plasma or serum. This assay has a minimum analytical sensitivity limit of 1.2 U/ml.
Herpes simplex virus (HSV) types 1 and 2 belong to the Herpesviridae family and are found to produce infection which can differ from mild stomatitis to disseminated and fatal disease. The infections caused by HSV 1 and 2 are known to differ greatly in their severity and clinical manifestations. Some of the clinical conditions that have been linked with HSV infection include disseminated primary infection, vesicular skin eruptions, keratitis, gingivostomatitis, aseptic meningitis, encephalitis, genital tract infections and neonatal herpes. HSV 1 is usually closely linked with orolabial infection but there is also evidence of genital infection among certain populations. Whereas, HSV 2 has been found to cause primarily urogenital infections and is usually exclusively only occurring in adults. The diagnosis HSV infections is routinely made based on clinical findings and supported by laboratory testing using PCR or viral culture. For typing of HSV 1/HSV 2 indirect immunofluorescence or Western blots can be performed. The diagnosis of the primary infection by HSV 1 and HSV 2 can be identified by a significant elevation of IgG within 6 to 10 days following infection.
The minimum detection sensitivity level of IgG antibodies directed against herpes simplex virus 1 and 2 (HSV 1 and 2 IgG) using current human HSV 1/2 IgG ELISA kit was 1.2 U/ml. The dynamic range for this assay is 1.0 – 200.0 U/ml.
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- Full Name: Herpes Simplex Virus 1/2 IgG ELISA Kit
- Reactivity: Human
- Sample Type: Serum, Plasma
- Sensitivity: 1.2 U/ml