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Herpes Simplex 1 IgM ELISA Kit

  • Created on the 22 August, 2017.

BACKGROUND

Infections with are due to herpes simplex virus are commonly referred to as herpes and these can be caused by either HSV-1 or HSV-2. HSV-1 is a highly contagious infection, which is acquired during childhood and the infection can be lifelong. The vast majority of HSV-1 infections are found to be oral herpes (also known as orolabial, oral-facial and oral-labial herpes), a proportion of HSV-1 infections are also genital herpes (infections in the genital and anal area). Infected persons will usually experience a burning, tingling or itching sensation around their mouth, which in majority of cases is before the appearance of sores.  One of the “gold standard” for diagnosing HSV infections is through the isolation of the virus in tissue culture, following by either western blotting or indirect immunofluorescence.

INTENDED USE

Human HSV-1 IgM ELISA kit can be used for measuring in-vitro quantitative concentrations of human IgM antibodies against herpes simplex virus-1 (HSV-1) in plasma or serum. This assay has a minimum analytical sensitivity limit of 1.06 U/ml.

SENSITIVITY

The minimum detection sensitivity level of human herpes simplex virus-1 (HSV-1) IgM using this human HSV-1 IgM ELISA kit was 1.06 U/ml. The dynamic assay range for this kit is 1.0 – 100.0 U/ml.

REFERENCES

  1. Analysis of the IgM and IgG antibody response against herpes simplex virus type 1 (HSV-1) structural and nonstructural proteins. J Med Virol. (1987) 23 (2): 135-50. Kühn J.E., et al.
  2. Evaluation of commercial herpes simplex virus-IgG and IgM enzyme immunoassays. J Virol Methods. (2014) 199: 29-34. Liermann K., et al.
  3. Comparison of several ELISA tests for detecting the presence of IgG and IgM against herpes simplex viruses. Microbios. (2000) 103 (405): 127-32. Gutiérrez J., et al.
  4. Reactivated herpes simplex infection increases the risk of Alzheimer’s disease. Alzheimers Dement. (2015) 11 (6): 593-9. Lövheim H., et al.

ADDITIONAL INFORMATION

  • Full Name: Herpes Simplex Virus 1 IgM ELISA Kit
  • Reactivity: Human
  • Sample Type: Serum, Plasma
  • Sensitivity: 1.06 U/ml

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