Human EBV VCA IgA ELISA kit is intended for detecting in-vitro quantitative amounts of human IgA antibodies to Epstein–Barr virus viral-capsid antigen (EBV VCA IgA) using serum and plasma. This assay has a minimum analytical sensitivity limit of 1.0 U/ml.
Epstein–Barr virus viral-capsid antigen (EBV-VCA) has an important role in providing the viral capsid of the Epstein–Barr virus (EBV). This antigen is targeted by anti-VCA antibodies and these antibodies are crucial in the diagnosis of infectious mononucleosis using many different serology testing methods. Elevated levels of anti-VCA IgG antibodies is a good indicator of prior infection whereas elevated levels of anti-VCA IgM can indicate acute infection. The anti-VCA IgM appears early during an EBV infection and it tends to disappear between 4-6 weeks, whereas anti-VCA IgG is present during the acute phase of EBV infections (peaks between 2-4 weeks and persist throughout a person life). Clinical findings of infectious mononucleosis can be identified in conjunction with the appearance of IgM and IgG anti-VCA antibodies. Also, for primary infections, the sensitivity of IgM and IgG anti-VCA testing are regarded as being 100% reliable.
The minimum detection sensitivity level of IgA antibodies against Epstein–Barr virus viral-capsid antigen (EBV-VCA-IgA) using current human EBV VCA IgA ELISA kit was 1.0 U/ml. The dynamic range for this assay is 1.0 – 125.0 U/ml.
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- Full Name: EBV VCA IgA ELISA Kit
- Reactivity: Human
- Sample Type: Plasma, Serum
- Sensitivity: 1.0 U/ml