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EBV EA (Early Antigen) IgG ELISA Kit

  • Created on the 18 July, 2017.

BACKGROUND

Epstein–Barr virus (EBV) is a member of the herpes family of viruses, it can also be called human herpesvirus 4 (HHV-4). The majority of the infections for EBV occur via oral transfer of saliva or genital secretion, many of these viral infections have also been strongly associated to a number of different autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, Sjögren’s syndrome and dermatomyositis. The detection of early antigen (EA) is quite often used to indicate an active infection, since EBV EA is linked to many acute phase illness and majority of these become undetectable after 3-6 months. Laboratory procedure such as ELISA assays and blood test are particularly useful in distinguishing a recent from a past EDV infection.

INTENDED USE

Human EBV EA-IgG ELISA kit is designed for measuring in-vitro quantitative amounts of human IgG antibodies against Epstein–Barr virus early antigen (EBV EA) in serum or plasma. This assay has a minimum analytical sensitivity limit of 1.37 U/ml.

SENSITIVITY

The minimum detection sensitivity level of human Epstein–Barr virus early antigen (EBV EA) IgG using this human EBV EA-IgG ELISA kit was 1.37 U/ml. The dynamic assay range for this kit is 1.0 – 150.0 U/ml.

REFERENCES

  1. Significance of plasma IgA and IgG antibodies to Epstein-Barr virus early and viral capsid antigens in Thai nasopharyngeal carcinoma. Asian Pac J Cancer Prev. (2003) 4 (2): 113-8. Tiwawech D., et al.
  2. Enzyme-linked immunosorbent assay for IgG antibodies to Epstein-Barr virus-associated early antigens and viral capsid antigen. J Immunol Methods. (1984) 67 (2): 225-33. Dölken G., et al.
  3. Avidities of IgG directed against viral capsid antigen or early antigen: useful markers for significant Epstein-Barr virus serology. J Med Virol. (1994) 43 (3): 238-44. Andersson A., et al.
  4. Antibodies to Epstein-Barr virus-induced early antigens in blood donors. Acta Virol. (1989) 33 (4): 344-8. Wohlrabe P., et al.

ADDITIONAL INFORMATION

  • Full Name: EBV EA (Early Antigen) IgG ELISA Kit
  • Reactivity: Human
  • Sample Type: Plasma, Serum
  • Sensitivity: 1.37 U/ml

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