- Created on the 13 July, 2017.
Human Chagas IgG ELISA kit can be used for analysing in-vitro quantitative concentrations of IgG antibodies to Chagas (Trypanosoma cruzi) in human serum and plasma samples. This assay has a minimum analytical sensitivity limit to a diagn. 99%.
Chagas disease is known to occur predominately in the continental part of Latin America and it is a life threatening illness that is caused by the protozoan parasite known as Trypanosoma cruzi (T. cruzi). It is estimated that around 6-7 million people worldwide are infected by this parasite, it is mainly vector borne transmitted by either contact with urine or faeces of triatomine bugs. The Chagas disease is presents itself in 2 phases. The initial acute phase (lasts two months). Where there is a high number of parasites which are circulating in the blood but the symptoms are often absent or mild and also non-specific. The second chronic phase, where the parasite is located in the digestive muscles and heart. This leads to cardiac disorders, digestive disorders (typically enlarged oesophagus and colon), neurological and many other mixed alterations. In the later years the infection can cause sudden death due to cardiac arrhythmias or heart failure because of the constant destruction of the heart muscle and the nervous system.
The minimum detection sensitivity level of IgG antibodies to Chagas (Trypanosoma cruzi, T. cruzi) IgG using current human Chagas IgG ELISA kit was diagn. 99%. The dynamic range for this assay was to a specific cut-off point.
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- Full Name: Chagas (Trypanosoma Cruzi) IgG ELISA Kit
- Reactivity: Human
- Sample Type: Plasma, Serum
- Sensitivity: diagn. 99%