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Carcinoembryonic Antigen (CEA) ELISA Kit

  • Created on the 11 May, 2017.

BACKGROUND

Carcinoembryonic Antigen (CEA) is a glycoprotein which is 200 kD and is mainly involved in cell adhesion. It is normally only produced during fetal development within the gastrointestinal tissue and the production stop immediately before birth. CEA was first discovered in human colon cancer tissue extracts and it has been later identified that the level of CEA also correlates with the tumor stage. There have a number of tumors which are now associated with elevated levels of CEA and these include stomach, lung, colon, breast gullet and pancreatic carcinomas. However, CEA measurement is predominately used as a tumor marker in order to monitor colorectal cancer treatment, staging, localise cancer spread and to identify recurrences.

INTENDED USE

Human CEA ELISA kit can be used for analysing in vitro quantitative amounts of carcinoembryonic antigen in human serum. This assay has a minimum sensitivity limit of < 0.596 ng/ml.

SENSITIVITY

The minimum detection sensitivity level of human CEA using this human carcinoembryonic antigen ELISA kit was < 0.596 ng/ml. The dynamic assay range for this kit is 3.0 – 100.0 U/ml.

REFERENCES

  1. CEA – a predictor for pathologic complete response after neoadjuvant therapy for rectal cancer. Dis Colon Rectum. (2013) 56 (7): 859-68. Wallin U., et al.
  2. Carcinoembryonic antigen (CEA) as tumor marker in lung cancer. Lung Cancer. (2012) 76 (2): 138-43. Review. Grunnet M. and Sorensen J.B.
  3. Postsurgical surveillance for recurrence of UICC stage I colorectal carcinoma: is follow-up by CEA justified? Hepatogastroenterology. (2005) 52 (62): 444-9. Yamamoto S., et al.
  4. The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. Semin Cancer Biol. (1999) 9 (2): 67-81. Review. Hammarström S.

ADDITIONAL INFORMATION

  • Full Name: Carcinoembryonic Antigen (CEA) ELISA Kit
  • Reactivity: Human
  • Sample Type: Serum
  • Sensitivity: 0.596 ng/ml

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