- Created on the 6 February, 2017.
Bone morphogenetic protein-2 (BMP-2, BMP 2A) is a member of the transforming growth factor beta (TGF-beta) superfamily of proteins. BMP-2 is like the other bone morphogenetic proteins and is involved in the development of cartilage and bone formation during embryogenesis. It is also involved in epithelial to mesenchymal transition, cardiac cell differentiation, induces p38 mitogen-activated protein kinase (MAPK), medulloblastoma cell and retinoid-induced apoptosis.
Bone morphogenetic proteins (BMPs) have an important function in promoting osteogenesis and currently there are clinical trials that are underway to evaluate the ability of certain BMPs to promote spinal fusion and fracture-healing. This ELISA assay uses a standard which is a recombinant human BMP-2 that constitutes a dimer of two chains of 114 amino acids with a total molecular mass of 26KDa.
Human BMP-2 ELISA kit is a reliable quantitative procedure for measuring bone morphogenetic protein-2 (BMP-2) in human serum, plasma, cell culture supernatant, tissue lysates and body fluids. This assay has a minimum sensitivity detection limit of < 1.0 pg/ml.
The minimum sensitivity detection limit of bone morphogenetic protein-2 (BMP-2) using this human BMP-2 ELISA kit was approximately < 1.0 pg/ml. The dynamic assay range for this kit is 15.6 – 1000.0 pg/ml.
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- Full Name: Bone Morphogenetic Protein-2 (BMP-2) ELISA Kit
- Reactivity: Human
- Sample Type: Serum, Plasma, Tissue Lysates, Cell Culture Supernatant, Body Fluids
- Sensitivity: < 1.0 pg/ml