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Anti-Ovarian Antibody ELISA Kit

  • Created on the 26 May, 2017.

BACKGROUND

Anti-ovarian antibodies are found to be responsible for interfering with fertility and ovulation, there are many different types and each one is found to be affecting specific functions of the ovaries. One of the most common antibodies are one that target the eggs (ova) and the ovarian cells. Anti-ovarian antibodies can be predominately discovered in women with premature ovarian failure and unexplained infertility. People suffering from endometriosis, Addison’s Disease and thyroid disease also display elevated levels of anti-ovarian antibodies. Recent research also indicated that they may be linked with higher rates of IVF treatment failure, poor implantation and poor response to hormone therapy. The use of human ovary antibody ELISA procedures is highly recommended in order to monitor disorders of ovarian failure and fertility. This procedure can also be applied in clinical practices for the confirmation or the exclusion of antibodies against ovarian tissues being responsible for fertility problems.

INTENDED USE

Human anti-ovarian Ab ELISA kit can be used to measure antibodies against ovary antigens using human serum samples. This assay has a minimum analytical sensitivity limit of 6.0 U/ml.

Mixture of ovary proteins are bound to the surface of the wells of the ELISA plate.

SENSITIVITY

The minimum detection sensitivity level of human anti-ovarian antibody using this human anti-ovarian Ab ELISA kit was 6.0 U/ml. The dynamic assay range for this kit is 6.0 – 100.0 U/ml.

REFERENCES

  1. Multiplicity of molecular and cellular targets in human ovarian autoimmunity: an update. J Assist Reprod Genet. (2010) 27 (9-10): 519-24. Review. Pires E.S.
  2. Can anti-ovarian antibody testing be useful in an IVF-ET clinic? J Assist Reprod Genet. (2011) 28 (1): 55-64. Pires E.S., et al.
  3. Premature ovarian failure. Hum Reprod Update. (2005) 11 (4): 391-410. Review. Goswami D. and Conway G.S.
  4. The role of genetic and autoimmune factors in premature ovarian failure. J Assist Reprod Genet. (2013) 30 (5): 617-22. Shamilova N.N., et al.
  5. Radioimmunotherapy of ovarian cancer. Int J Biol Markers. (1993) 8 (3): 187-91. Review. Crippa F.

ADDITIONAL INFORMATION

  • Full Name: Anti-Ovarian Antibody ELISA Kit
  • Reactivity: Human
  • Sample Type: Serum
  • Sensitivity: 6.0 U/ml

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