- Created on the 31 May, 2017.
Anti-double stranded DNA (anti-dsDNA) have been vital in the diagnosis of systemic lupus erythematosus (SLE) and they are produced by the immune system when it fails to differentiate self from non-self. Majority of patient with SLE are found to display antibodies against dsDNA for IgG, IgA and IgM class within their sera, these autoantibodies are usually associated with lupus nephritis. Also, many studies have demonstrated the link of these subclass with certain parameters of the disease activity for example consumption of complement component C3, elevated erythrocyte sedimentation rate, acral necrosis, erythema, cutaneous vasculitis.
Human ds-DNA screen ELISA kit can be used for analysing in vitro quantitative levels of IgA, IgG and IgM autoantibodies to double stranded DNA (dsDNA) in human serum or plasma samples. This assay has a minimum analytical sensitivity limit of 1.0 U/ml.
The minimum detection sensitivity level of human double stranded DNA antibodies (dsDNA screen) using this human ds-DNA screen ELISA kit was 1.0 U/ml. The dynamic assay range for this kit is 12.5 – 200.0 U/ml.
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- Full Name: Anti-dsDNA Screen ELISA Kit
- Reactivity: Human
- Sample Type: Serum, Plasma
- Sensitivity: 1.0 U/ml