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17-Beta Estradiol E2 ELISA Kit

  • Created on the 15 February, 2017.

BACKGROUND

17-beta-estradiol (E2) is produced predominately by the placenta or the ovary, with smaller amounts made in the testes or the adrenals and testes or the adrenals. It has a molecular weight of 272.4 Da and is a C18 steroid hormone which is in equilibrium with estrone and it can be converted to estriol by the liver or the placenta. There are a number of clinical applications where the determination of E2 levels has been particularly useful. There include the measurement of estradiol levels in peritoneal fluid, serum and follicular fluid as a vital biochemical tool that is routinely used for investigating sexual diseases, tumors, fertility and disorders of hypothalamic/pituitary/gonadal axis.

INTENDED USE

Human 17-beta estradiol E2 ELISA kit is a reliable quantitative procedure for measuring 17-beta estradiol E2 (17β-estradiol E2) in human serum and plasma. This assay has a minimum sensitivity detection limit of 2.0 pg/ml.

SENSITIVITY

The minimum sensitivity detection limit of 17-beta estradiol E2 (17β-estradiol E2) using this human 17-beta estradiol E2 ELISA kit was approximately 5.0 pg/ml. The dynamic assay range for this kit is 13.0 – 935.0 pg/ml.

REFERENCES

  1. Subcellular concentrations of estrone, estradiol, androstenedione and 17-β-hydroxysteroid dehydrogenose (17BOH-SOH) Activity in malignant and non-malignant human breast tissues. Int. J. Cancer (1987) 40: 305-308. Metha R.R.
  2. Outcome of in vitro fertilization in women with low response to ovarian stimulation. Fertil. and Steril. (1987) 47 (5): 812-815. Pellicer A., et al.
  3. Dose dependent response of symptoms, pituitary, and bone to transferma oestrogen in postmenopausal women. Br.Med. (1986) 293: 1337-1339. Selby et al.
  4. Ovarian and adrenal contribution to peripheral androgens during the menstrual cycle. J. Clin. Endocrinol. Metab. (1974) 39: 340-346. Abraham G.E.

ADDITIONAL INFORMATION

  • Full Name: 17-Beta Estradiol E2 ELISA Kit
  • Reactivity: Human
  • Sample Type: Serum, Plasma
  • Sensitivity: 5.0 pg/ml

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